If using a dermaroller at home, a person should follow the steps described here:
- remove the dermaroller from its container
- spray it with alcohol solution and wash with warm water to sterilize
- prepare the skin for treatment with an antiseptic or saline wash
- hold the skin taughtroll over each section, once up and down, once side to side, and once diagonally
- bathe the skin with saline after the skin has reddened
- spray the dermaroller with alcohol solution and wash with warm water to sterilize
- leave the dermaroller to dry
- put back in the storage case

When using the dermaroller on the face, a person should treat five sections of the face in turn. These sections are:
- top right of forehead and cheek
- top left of forehead and cheek
- right under eye and lower cheek
- left under eye and lower cheek
- around the mouth
After using the dermaroller, a person can apply serums or moisturizers to their skin. The treatment is often used as a delivery system to maximize the effects of these lotions.
It is thought that these applications are absorbed much more easily and deeply by skin treated by a dermaroller than untreated skin.
People should avoid a dermaroller if they have a history of blood-clotting problems, or are using accutane or other medical treatments.
Dermarollers should not be used on areas of skin that have eczema, sunburn, or cold sores. Anywhere there are moles, skin inflammation, or rosacea should also be avoided.

Dermarollers should not be used on areas of skin that have eczema, sunburn, or cold sores. Anywhere there are moles, skin inflammation, or rosacea should also be avoided.